Journal of the American College of Certified Wound Specialists
Volume 1, Issue 4 , Pages 117-120 , December 2009

In Vitro Study of Sustained Antimicrobial Activity of a New Silver Alginate Dressing

  • Colin Bradford, HTec

      Affiliations

    • Advanced Medical Solutions Ltd, Winsford, Cheshire, UK
    • Corresponding Author InformationCorresponding author.
    • ,
  • Richard Freeman, PhD

      Affiliations

    • Advanced Medical Solutions Ltd, Winsford, Cheshire, UK
    • ,
  • Steven L. Percival, PhD

      Affiliations

    • Advanced Medical Solutions Ltd, Winsford, Cheshire, UK

References 

  1. Wasiak J, Cleland H, Campbell F. Dressings for superficial and partial thickness burns. Cochrane Database Syst Rev. 2008;8(4):CD002106
  2. Lansdown ABG. A review of silver in woundcare: facts and fallacies. Br J Nurs. 2004;13:6–19
  3. Lansdown ABG. Silver 1: its antimicrobial properties and mechanism of action. J Wound Care. 2002;11:125–131
  4. Lo SF, Chang CJ, Hu WY, Hayter M, Chang YT. The effectiveness of silver-releasing dressings in the management of non-healing chronic wounds: a meta-analysis. J Clin Nurs. 2009;18(5):716–728
  5. Lawrence JC. The bacteriology of burns. J Hosp Infect. 1985;6(B):3–17
  6. Hill KE, Davies CE, Wilson MJ, Stephens P, Harding KG, Thomas DW. Molecular analysis of the microflora in chronic venous leg ulceration. J Med Microbiol. 2003;52(Pt 4):365–369
  7. Davies CE, Wilson MJ, Hill KE, et al. Use of molecular techniques to study microbial diversity in the skin: chronic wounds re-evaluated. Wound Repair Regen. 2001;9:332–340
  8. Percival SL, Bowler PG: Understanding the effects of bacterial communities and biofilms on wound healing. World Wide Wounds. 2004. July. Available at www.worldwidewounds.com. Accessed July 2009.
  9. Andersen A, Hill KE, Stephens P, Thomas DW, Jorgensen B, Krogfelt KA. Bacterial profiling using skin grafting, standard culture and molecular bacteriological methods. J Wound Care. 2007;16(4):171–175
  10. Cochrane CA, Freeman K, Woods E, Welsby S, Percival SL. Biofilm evidence and the microbial diversity of horse wounds. Can J Microbiol. 2009;55(2):197–202
  11. Leaper DJ. Silver dressings: their role in wound management. Int Wound J. 2006;3(4):282–294
  12. Kang CI, Kim SH, Park WB, et al. Bloodstream infections caused by antibiotic-resistant gram-negative bacilli: risk factors for mortality and impact of inappropriate initial antimicrobial therapy on outcome. Antimicrob Agents Chemother. 2005;49:760–766
  13. Guggenheim M, Zbinden R, Handschin AE, Gohritz A, Altintas MA, Giovanoli P. Changes in bacterial isolates from burn wounds and their antibiograms: a 20- year study (1986-2005). Burns. 2009;35(4):553–560
  14. Gardner SE, Frantz RA, Saltzman CL, Dodgson KJ. Staphylococcus aureus is associated with high microbial load in chronic wounds. Wounds. 2004;16:251–257
  15. Aufiero B, Duanmu Z, Guo M, Meduri NB, Murakawa GJ, Falkow S. Staphylococcus aureus infection of human primary keratinocytes. J Dermatol Sci. 2004;36(3):173–175
  16. Wright AE, Fleming A, Colebrook L. The conditions under which the sterilisation of wounds by physiological agency can be obtained. Lancet. 1918;i:831–838

 Conflict of interest: The authors are all employees of Advanced Medical Solutions Ltd.

 1ACSD is Maxorb Extra Ag, a registered trademark of Medicine Industries, Inc.

 2HSD is Aquacel, registered trademark of ConvaTec, Ltd.

PII: S1876-4983(09)00119-2

doi: 10.1016/j.jcws.2009.09.001

Journal of the American College of Certified Wound Specialists
Volume 1, Issue 4 , Pages 117-120 , December 2009

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